Wilson had to go under the knife to repair a torn patellar tendon, an injury that will likely keep him off the field for the second straight year, according to Cleveland.com.
A fourth-round draft pick of the Browns in 2017 out of the University of Houston, Brown missed his rookie campaign due to a fractured kneecap.
Cleveland used its second first-round pick this year -- No. 4 overall -- to take cornerback Denzel Ward out of Ohio State. Ward already is practicing with the first team.
The Browns also acquired cornerback Damarious Randall from the Green Bay Packers in March and drafted defensive back Simeon Thomas out of Louisiana Lafayette in the sixth round.